Correlation between Serum Albumin Level and IgG Level in Minimal Change Nephrotic Syndrome
Journal of the Korean Society of Pediatric Nephrology
;
: 16-23, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-220802
ABSTRACT
PURPOSE:
Hypogammaglobulinemia has been observed in nephrotic syndrome, but its pathophysiology remains unknown. We evaluated the relationship between the serum IgG and albumin levels for children with minimal change nephrotic syndrome(MCNS).METHODS:
The levels of immunoglobulin G(IgG), albumin and total cholesterol of a total of 46 children with MCNS(proteinuria >40 mg/m2/h, and serum albumin level <2.5 g/dL) were analyzed.RESULTS:
The mean values of albumin, IgG and total cholesterol in MCNS children were 1.7+/-0.3 g/dL, 368+/-143 mg/dL and 431+/-78 mg/dL, respectively. There was an inverse correlation between the albumin values and the total cholesterol values(r=0.68, P=0.0001), whereas there was a direct-proportional correlation between albumin values and the IgG values(r=0.4, P=0.01).CONCLUSION:
The IgG level is associated with albumin level, and it may reflect the severity of urinary protein loss in MCNS. Further studies are needed to evaluate this phenomenon.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Imunoglobulina G
/
Imunoglobulinas
/
Albumina Sérica
/
Colesterol
/
Agamaglobulinemia
/
Nefrose Lipoide
/
Síndrome Nefrótica
Limite:
Criança
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Pediatric Nephrology
Ano de publicação:
2007
Tipo de documento:
Artigo
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