Chemical Constituents from Buddleja officinalis and Their Inhibitory Effects on Nitric Oxide Production
Natural Product Sciences
;
: 129-133, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-221213
ABSTRACT
Bioactivity-guided fractionation of a methanolic extract of Buddleja officinalis led to the isolation of two monoterpenes, crocusatin M (1), crocusatin C (2), a flavonoid, acacetin (3), three lignans, lariciresinol (4), pinoresinol (5), and syringaresinol (6), and two triterpenoidal saponins, mimengoside B (7) and songarosaponin A (8). The structures of isolates were identified based on 1D-, 2D-NMR, and MS data analysis. All isolates were tested for their inhibition on LPS-induced NO production in RAW 264.7 cells. As a result, mimengoside B (7) and songarosaponin A (8) showed a mild inhibitory activity of NO production.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Saponinas
/
Estatística como Assunto
/
Lignanas
/
Buddleja
/
Monoterpenos
/
Metanol
/
Óxido Nítrico
Idioma:
Inglês
Revista:
Natural Product Sciences
Ano de publicação:
2016
Tipo de documento:
Artigo
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