Clinical and magnetic resonance imaging features of compressive cervical myelopathy with traumatic intervertebral disc herniation in cynomolgus macaque (Macaca fascicularis) / 한국실험동물학회지
Laboratory Animal Research
;
: 267-271, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-221829
ABSTRACT
Intervertebral disc herniation (IVDH) with nucleus pulposus extrusion, traumatic or not, is a devastating clinical condition accompanied by neurological problems. Here we report a cynomolgus macaque suffering from acute and progressive neurological dysfunction by a blunt trauma due to neck collar, an animal handling device. Tetraplegia, urinary incontinence, decreased proprioception, and imperception of pain were shown on physical and neurological examinations. MRI sagittal T2 weighted sequences revealed an extensive protrusion of disc material between C2 and C3 cervical vertebra, and this protrusion resulted in central stenosis of the spinal cord. Histopathologic findings showed a large number of inflammatory cells infiltrated at sites of spinal cord injury (SCI). This case is the first report of compressive cervical SCI caused by IVDH associated with blunt trauma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Propriocepção
/
Quadriplegia
/
Medula Espinal
/
Doenças da Medula Espinal
/
Traumatismos da Medula Espinal
/
Coluna Vertebral
/
Incontinência Urinária
/
Imageamento por Ressonância Magnética
/
Constrição Patológica
/
Disco Intervertebral
Limite:
Animais
Idioma:
Inglês
Revista:
Laboratory Animal Research
Ano de publicação:
2016
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS