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Disseminated Cytomegalovirus Infection and Protein Losing Enteropathy as Presenting Feature of Pediatric Patient with Crohn's Disease / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition ; : 60-65, 2015.
Artigo em Inglês | WPRIM | ID: wpr-222170
ABSTRACT
We report a pediatric patient admitted with abdominal pain, diffuse lower extremity edema and watery diarrhea for two months. Laboratory findings including complete blood count, serum albumin, lipid and immunoglobulin levels were compatible with protein losing enteropathy. Colonoscopic examination revealed diffuse ulcers with smooth raised edge (like "punched out holes") in the colon and terminal ileum. Histopathological examination showed active colitis, ulcerations and inclusion bodies. Immunostaining for cytomegalovirus was positive. Despite supportive management, antiviral therapy, the clinical condition of the patient worsened and developed disseminated cytomegalovirus infection and the patient died. Protein losing enteropathy and disseminated cytomegalovirus infection a presenting of feature in steroid-naive patient with inflammatory bowel disease is very rare. Hypogammaglobulinemia associated with protein losing enteropathy in Crohn's disease may predispose the cytomegalovirus infection in previously healthy children.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Enteropatias Perdedoras de Proteínas / Úlcera / Contagem de Células Sanguíneas / Imunoglobulinas / Albumina Sérica / Doenças Inflamatórias Intestinais / Doença de Crohn / Dor Abdominal / Corpos de Inclusão / Colite Limite: Criança / Humanos Idioma: Inglês Revista: Pediatric Gastroenterology, Hepatology & Nutrition Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Enteropatias Perdedoras de Proteínas / Úlcera / Contagem de Células Sanguíneas / Imunoglobulinas / Albumina Sérica / Doenças Inflamatórias Intestinais / Doença de Crohn / Dor Abdominal / Corpos de Inclusão / Colite Limite: Criança / Humanos Idioma: Inglês Revista: Pediatric Gastroenterology, Hepatology & Nutrition Ano de publicação: 2015 Tipo de documento: Artigo