A Case of Polyglandular Autoimmune Syndrome
Journal of the Korean Pediatric Society
; : 1299-1223, 1998.
Article
em Ko
| WPRIM
| ID: wpr-222464
Biblioteca responsável:
WPRO
ABSTRACT
When dysfunction of two or more endocrine glands occurs in association with circulating organ specific antibodies directed against the involved glands, the term polyglandular autoimmune (PGA) syndrome is applied. This syndrome is usually classified into three groups. The autoimmune nature of this disease has been based on the presence of lymphocytic infiltration of the affected glands, organ specific autoantibody in serum, cellular immune defects and association with HLA DR/DQ genes. A 12-year-old girl developed PGA syndrome, type III manifesting Grave's disease and insulin-dependent diabetes mellitus. The thyroid microsomal Ab, TSH receptor Ab and pancreatic islet cell Ab were positive. She should be observed for the possible development of adrenal insufficiency and/or other autoimmune disease.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Doenças Autoimunes
/
Glândula Tireoide
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Receptores da Tireotropina
/
Ilhotas Pancreáticas
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Insuficiência Adrenal
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Diabetes Mellitus Tipo 1
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Glândulas Endócrinas
/
Anticorpos
Limite:
Child
/
Female
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Humans
Idioma:
Ko
Revista:
Journal of the Korean Pediatric Society
Ano de publicação:
1998
Tipo de documento:
Article