Effect of irradiation on the healing of extraction sockets in diabetic rats / 대한구강악안면방사선학회지
Korean Journal of Oral and Maxillofacial Radiology
;
: 5-14, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-222556
ABSTRACT
PURPOSE:
To observe the histologic pattern of healing in molar tooth extraction sockets of streptozotocin-induced diabetic rats following irradiation. MATERIALS ANDMETHODS:
Mature Sprague-Dawley rats were divided into three groups control, diabetic, and diabetic-irradiated groups. Diabetes mellitus was induced by injecting streptozotocin. Control rats were injected with a citrate buffer only. After 5 days, the right maxillary first molar was extracted under general anesthesia from each of the rats. After the extraction, rats in the diabetic-irradiated group were irradiated with a single absorbed dose of 10 Gy to the head and neck region. The rats were killed at 1, 3, 7, 14, 21, and 28 days after treatment. Tissue sections were stained with hematoxylineosin and Masson's trichrome.RESULTS:
In the diabetic and diabetic-irradiated groups, the early healing process of the socket extraction was similar to the control group, but bone formation was delayed at 7 days after the treatment. In the diabetic-irradiated group, alveolar bone surrounding the extraction socket showed signs of necrosis at 3 days after treatment, and hemorrhage was observed in connective tissue within the extraction socket at 14 days after treatment.CONCLUSION:
This experiment revealed that the healing process of the extraction socket was severely delayed and retarded by irradiation in the diabetic state.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteogênese
/
Extração Dentária
/
Cicatrização
/
Irradiação Craniana
/
Ratos Sprague-Dawley
/
Estreptozocina
/
Tecido Conjuntivo
/
Ácido Cítrico
/
Diabetes Mellitus
/
Cabeça
Limite:
Animais
Idioma:
Coreano
Revista:
Korean Journal of Oral and Maxillofacial Radiology
Ano de publicação:
2003
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS