The Experience and Management of Two Cases of Metformin-associated Lactic Acidosis
Journal of the Korean Society of Emergency Medicine
;
: 771-774, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-223350
ABSTRACT
Metformin, a dimethylbiguanide, is an oral antihyperglycemic drug used in treatment of type 2 diabetes mellitus. It has been reported that metformin may be associated with lactic acidosis in patients with clinical conditions such as renal failure and heart failure. Metformin-associated lactic acidosis (MALA) is a rare, but serious complication with a mortality rate of approximately 30~50%. Therefore, an aggressive treatment strategy including hemodialysis is recommended for these patients. Although continuous renal replacement therapy (CRRT) has been administered in hemodynamically unstable patients with MALA, there are few case reports describing the use of CRRT as a therapeutic modality in Korea. Here, we describe the case histories of two MALA patients who underwent treatment with CRRT.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Acidose
/
Acidose Láctica
/
Mortalidade
/
Diálise Renal
/
Terapia de Substituição Renal
/
Diabetes Mellitus Tipo 2
/
Insuficiência Renal
/
Insuficiência Cardíaca
/
Coreia (Geográfico)
/
Metformina
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of the Korean Society of Emergency Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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