The Change of Diastolic Tissue Doppler Velocity of Mitral Annulus: the Differences between Septal and Lateral Annulus

ABSTRACT

BACKGROUND AND OBJECTIVES: Mitral annulus velocity profile during diastole may provide additional information about left ventricular diastolic function. This study assessed the change of mitral annulus velocity profile during diastole with aging and the differences between septal and lateral annulus. SUBJECTS AND METHODS: Simultaneous measurements of annular velocity at both septal and lateral annulus were performed in 171 consecutive patients who had no evidence of hypertension, diabetes, other heart diseases and rhythm disturbances. RESULTS: The mean age of the subjects was 44.6+/-15.2 years (range16-74) and male 93, female 68. The Em and Em/Am were well correlated with age negatively, irrespective of the position of sample volume (Em(septum)r=-0.75, p<0.0001, Emlateralr=-0.78, p<0.0001;Em/Am(septum)r=-0.72, p<0.0001, Em/Am(lateral)r=-0.71, p<0.0001). The Em and Em/Am were significantly decreased in septum compared with lateral annulus (Em9.9+/-3.1 vs. 13.5+/-4.1, p<0.0001;Em/Am1.15+/-0.57 vs. 1.53+/-0.75, p<0.0001). CONCLUSION: The indices of mitral annular velocity were well correlated with aging negatively. And the mitral annular velocity was decreased significantly at the septum compared with lateral annulus.