Development of (1)H-(31)P Animal RF Coil for pH Measurement Using a Clinical MR Scanner
Journal of the Korean Society of Magnetic Resonance in Medicine
;
: 52-58, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-223483
ABSTRACT
PURPOSE:
To establish a pH measurement system for a mouse tumor study using a clinical scanner, to develop the (1)H and (31)P radio frequency (RF) coil system and to test pH accuracy with phantoms. MATERIALS ANDMETHODS:
The (1)H and the (31)P surface coils were designed to acquire signals from mouse tumors. Two coils were positioned orthogonally for geometric decoupling. The pH values of various pH phantoms were calculated using the (1)H decoupled (31)P MR spectrum with the Henderson-Hasselbalch equation. The calculated pH value was compared to that of a pH meter.RESULTS:
The mutual coil coupling was shown in a standard S12. Coil coupling (S12) were -73.0 and -62.3 dB respectively. The signal-to-noise ratio (SNR) obtained from the homogeneous phantom (1)H image was greater than 300. The high resolution in vivo mice images were acquired using a (31)P-decoupled (1)H coil. The pH values calculated from the (1)H-decoupled (31)P spectrum correlated well with the values measured by pH meter (R(2)=0.97).CONCLUSION:
Accurate pH values can be acquired using a (1)H-decoupled (31)P RF coil with a clinical scanner. This two-surface coil system could be applied to other nuclear MRS or MRI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Imageamento por Ressonância Magnética
/
Razão Sinal-Ruído
/
Concentração de Íons de Hidrogênio
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of the Korean Society of Magnetic Resonance in Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS