Clinical value of serum vascular endothelial growth factor (VEGF) in ovarian diseases / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
; : 135-141, 2007.
Article
em Ko
| WPRIM
| ID: wpr-224168
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: The aim of this study was to evaluate the concentration of serum VEGF and its relationship with the clinical parameters and the tumor markers in ovarian diseases. METHODS: We measured the serum VEGF concentrations by ELISA in 76 patients with benign ovarian disease, as well as 9 normal volunteers, 4 patients with ovarian borderline malignancy and 53 patients with ovarian cancer. RESULTS: There is a significant statistical difference between the serum VEGF levels in patients with benign ovarian disease (157.7+/-197.8 pg/ml) and ovarian cancer (344.7+/-372.2 pg/ml) (p<0.005). CONCLUSION: Serum VEGF may help in the differential diagnosis between benign and malignant ovarian disease. We suggest that serum VEGF may be useful as a diagnostic tool in ovarian disease.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Doenças Ovarianas
/
Neoplasias Ovarianas
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Ensaio de Imunoadsorção Enzimática
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Biomarcadores Tumorais
/
Fator A de Crescimento do Endotélio Vascular
/
Diagnóstico Diferencial
/
Voluntários Saudáveis
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2007
Tipo de documento:
Article