Antithrombotic Therapy for Ischemic Stroke / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 1-12, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-224207
ABSTRACT
Ischemic stroke is among the principal causes of death and disability in the elderly. Although control of blood pressure, decreased cigarette smoking, and modified dietary habits are among important reasons for stroke decline, the use of antithrombotic therapy, rigorously prescribed. Several antiplatelet agents are approved to reduce the risk of recurrent stroke. Aspirin is the best-studied and most widely used antiplatelet agent for stroke prevention; it provides approximately 15% to 25% relatively risk reduction for secondary prevention of stroke or the major vascular death. Combining 2 antiplatelet agents with different mechanism of action was demonstrated to provide a substantial increase in efficacy in several studies. Anticoagulation should be considered first with potential cardiac sources of embolism. Heparin reduces development of erythrocyte-fibrin thrombi that form in regions of vascular stasis especially within the heart, in severely stenosed arteries sometimes engrafted on white thrombi, in acute arterial occlusion. Heparin should not be indiscriminately given to all acute brain ischemia patients, but may contribute to treatment of large artery occlusion and severe stenosis, cardiogenic embolism with a high acute recurrence risk, and dural sinus and cerebral venous thromobosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artérias
/
Recidiva
/
Pressão Sanguínea
/
Inibidores da Agregação Plaquetária
/
Heparina
/
Fumar
/
Isquemia Encefálica
/
Aspirina
/
Causas de Morte
/
Constrição Patológica
Tipo de estudo:
Estudo de etiologia
Limite:
Idoso
/
Humanos
Idioma:
Coreano
Revista:
Yeungnam University Journal of Medicine
Ano de publicação:
2003
Tipo de documento:
Artigo
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