Peritoneal Dialysis Associated Peritonitis and Empirical Antibiotics Therapy in Korean Children with Chronic Renal Failure
Journal of the Korean Society of Pediatric Nephrology
; : 213-220, 2008.
Article
em Ko
| WPRIM
| ID: wpr-225429
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: This study aims to verify the effectiveness of initial empirical antibiotic choice recommended by the International Society for Peritoneal Dialysis(ISPD) guide among Korean children. METHODS: We have collected data on peritonitis from January 2001 to December 2007 in Samsung Medical Center. RESULTS: Of the 42 patients, 48 episodes of peritonitis had occurred in 21 patients. The rate of peritonitis was one episode over 35.3 patient-months. Mean dialysis duration before peritonitis was 18.06+/-15.81 months. Gram-positive organisms accounted for 58.3% of all episodes. Of the gram-positive organisms, the most common pathogen was Staphylococcus aureus(29.2 %), the next common pathogens were Coagulase negative staphylococcus(14.6%) and Streptococcus species(6.3%). 35.7% of gram-positive pathogens were resistant to 1st cephalosporin. However, in patients younger than 4 years old, 50% of gram-positive pathogens were resistant to 1st generation cephalosporin. 10 episodes of peritonitis were methicillin-resistant and were treated by vancomycin. Of the gram-negative organisms, E. coli was the most common (8.3%). 64.8% of all pathogens were sensitive to cephalothin or ceftazidime. CONCLUSION: The empirical therapy with 1st generation cephalosporin and ceftazidime can be also effective to peritoneal dialysis associated peritonitis in Korean children. However, in patients younger than 4 years old, glycopeptide should be considered as the first empirical therapy in Korean children.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Peritonite
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Staphylococcus
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Staphylococcus aureus
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Streptococcus
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Vancomicina
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Ceftazidima
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Cefalotina
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Resistência a Meticilina
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Diálise Peritoneal
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Coagulase
Limite:
Child
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Humans
Idioma:
Ko
Revista:
Journal of the Korean Society of Pediatric Nephrology
Ano de publicação:
2008
Tipo de documento:
Article