One-Year Rehospitalization Rates of Inpatients with First-Episode Bipolar Mania Treated with Atypical Antipsychotics in Combination with Mood Stabilizers: A Preliminary Study / 대한정신약물학회지
Korean Journal of Psychopharmacology
;
: 137-143, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-225665
ABSTRACT
OBJECTIVE:
We compared the one-year rehospitalization rates of first-episode bipolar manic patients who were discharged while being treated with atypical antipsychotics in combination with mood stabilizers.METHODS:
We monitored the rehospitalization status of the first-episode bipolar manic patients who were discharged between 1 January 2003 and 31 December 2008 while they were taking risperidone (n=34), olanzapine (n=26) or quetiapine (n=32) in combination with mood stabilizers. Rehospitalizations were tracked over a 1-year period using the Kaplan-Meier method and Cox regression model was used to analyze covariates thought to affect time to rehospitalization.RESULTS:
The rehospitalization rates during the 1-year follow-up period for patients taking atypical antipsychotics plus mood stabilizers were 22.8% (n=21). There were no significant differences in rehospitalization estimated using the Kaplan-Meier formula among the patients treated with risperidone (29.4%), olanzapine (23.1%) or quetiapine (15.6%). The psychotic symptoms, previous depressive episodes, lower Global Assessment of Functioning (GAF) score at discharge and less length of first hospitalization contributed to the risk of rehospitalization.CONCLUSION:
The 1-year rehospitalization rates of first-episode bipolar manic patients taking risperidone, olanzapine, or quetiapine do not differ and the psychotic symptoms and previous depressive episodes affect time to rehospitalization.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Atletismo
/
Antipsicóticos
/
Benzodiazepinas
/
Transtorno Bipolar
/
Seguimentos
/
Risperidona
/
Dibenzotiazepinas
/
Fumarato de Quetiapina
/
Hospitalização
/
Pacientes Internados
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Psychopharmacology
Ano de publicação:
2010
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS