The First Case of Abacavir Hypersensitivity Associated with the HLA-B*57:01-Positive Allele in Korea / 감염과화학요법
Infection and Chemotherapy
;
: 399-402, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-226032
ABSTRACT
On the 12th day of abacavir treatment, a 39-year old HIV-infected male patient was admitted with fever, generalized rash, abdominal pain, and watery diarrhea that had persisted for five days. Results of blood tests indicated rapid progression of hepatitis and renal failure. The day after stopping anti-retroviral therapy, his fever subsided and his liver function began to normalize. He was clinically diagnosed with abacavir hypersensitivity and was found to carry the HLA-B*5701 allele. This is the first reported case of abacavir hypersensitivity associated with the presence of the HLA-B*5701 allele in Korea.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Didesoxinucleosídeos
/
Dor Abdominal
/
Diarreia
/
Alelos
/
Insuficiência Renal
/
Exantema
/
Febre
/
Testes Hematológicos
/
Hepatite
/
Hipersensibilidade
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Infection and Chemotherapy
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS