Comparison of Central Corneal Thickness and Anterior Chamber Depth Measured Using Three Different Devices

ABSTRACT

PURPOSE: To compare measurements of central corneal thickness (CCT) and anterior chamber depth (ACD) obtained using Galilei(TM), Pentacam(R) (Oculus, Wetzlar, Germany) and Lenstar(R) (Haag-Streit, Koeniz, Switzerland) and analyze the measurement agreements. METHODS: CCT and ACD were measured using Galilei(TM), Pentacam(R) and Lenstar(R) in 47 eyes of 25 healthy subjects. The measurements were compared among the 3 devices. RESULTS: The average CCT measurements using Galilei(TM), Pentacam(R) and Lenstar(R) were 552.6 +/- 29.41 microm, 543.9 +/- 30.50 microm and 537.5 +/- 30.26 microm, respectively. The measurements significantly correlated with each other (r > 0.9, p 0.9, p < 0.001), but were statistically significantly different (p = 0.034). The CCT 95% limits of agreement (LoA) between Galilei(TM) and Pentacam(R), Pentacam(R) and Lenstar(R) and Lenstar(R) and Galilei(TM) were 31.95 microm, 44.76 microm and 46.57 microm, respectively and 95% ACD LoA were 0.46 mm, 0.32 mm and 0.28 mm, respectively. CONCLUSIONS: CCT and ACD measured using the 3 devices were highly correlated with each other but the measurements were statistically different. Therefore, the measurements were not interchangeable and these differences should be considered in clinical use.