Fibrovascularization of Intraorbital Hydroxyapatite-Coated Alumina Sphere in Rabbits
Korean Journal of Ophthalmology
;
: 9-17, 2005.
Artigo
em Inglês
| WPRIM
| ID: wpr-226719
ABSTRACT
We investigated the fibrovascular ingrowth and fibrovascular tissue maturation of hydroxyapatite-coated, porous alumina sphere (Alumina sphere) in comparison with the hydroxyapatite sphere (HAp sphere) in rabbits. Alumina spheres and HAp spheres were implanted in the left orbits of 42 New Zealand white rabbits after enucleation. Fibrovascular ingrowth and maturation were graded from 1 to 5 at postoperative 1, 2, 3, 4, 8, 12 and 24 weeks. We defined 4 phases postoperative 1-2 weeks as phase I, 3-4 weeks as phase II, 8-12 weeks as phase III, and 24 weeks as phase IV. The grade was analyzed at each phases. There was no significant difference in fibrovascular ingrowth and maturation between the two groups at all 4 phases, except phase II at which the Alumina sphere showed significantly lower maturation grade (p< 0.05). We concluded that the Alumina sphere is an ideal orbital implant material and an ideal substitute for the HAp sphere in clinical practice.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Microscopia Eletrônica de Varredura
/
Enucleação Ocular
/
Durapatita
/
Neovascularização Fisiológica
/
Implantação de Prótese
/
Materiais Revestidos Biocompatíveis
/
Implantes Orbitários
/
Óxido de Alumínio
/
Fibroblastos
Limite:
Animais
Idioma:
Inglês
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
2005
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS