Assessment of Non-permeability of Gd-DTPA for Dynamic Susceptibility Contrast in Human Brain: A Preliminary Study Using Non-linear Curve Fitting
Journal of the Korean Society of Magnetic Resonance in Medicine
;
: 103-109, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-227811
ABSTRACT
To develop an advanced non-linear curve fitting (NLCF) algorithm for performing dynamic susceptibility contrast study of the brain. The first pass effects give rise to spuriously high estimates of Ktrans for the voxels that represent the large vascular components. An explicit threshold value was used to reject voxels. The blood perfusion and volume estimation were accurately evaluated in the T2*-weighted dynamic contrast enhanced (DCE)-MR images. From each of the recalculated parameters, a perfusion weighted image was outlined by using the modified non-linear curve fitting algorithm. The present study demonstrated an improvement of an estimation of the kinetic parameters from the DCE T2*-weighted magnetic resonance imaging data with using contrast agents.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Perfusão
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Meios de Contraste
/
Gadolínio DTPA
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Magnetic Resonance in Medicine
Ano de publicação:
2007
Tipo de documento:
Artigo
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