Two Cases of Upper Gastrointestinal Bleeding in Healthy Full Term Neonates

ABSTRACT

Upper gastrointestinal bleeding (UGIB) secondary to gastritis or peptic ulcer is unusual in neonates and possibly related to several risk factors such as intracranial hemorrhage, intracranial hypertension, congenital heart disease, perinatal asphyxia, respiratory failure and hypovolemia. It is even more unusual that healthy full term neonates get UGIB. Upper gastrointestinal endoscopy is indicated in neonates with persistent UGIB to identify the cause and location of bleeding. We report two cases of UGIB successfully treated with injection of epinephrine by means of endoscopy in healthy full term neonates. One infant had duodenal ulcer and the other had hemorrhagic gastritis.