Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury
Journal of Veterinary Science
;
: 79-81, 2006.
Artigo
em Inglês
| WPRIM
| ID: wpr-228005
ABSTRACT
Renal ischemia as a course of renal transplantation is a common cause of renal dysfunction as renal failure. The purpose of this study was to investigate the influence of ascorbic acid on blood urea nitrogen (BUN), creatinine (Cr) and resistive index (RI) for dog models with renal ischemia-reperfusion (I/R) injury. Renal ischemia was induced on 6 Beagle dogs. The left kidney was exposed to normothermic ischemia for a short period at 30 min followed by reperfusion. On the blood Cr level and RI, there was no significant difference comparing both groups. 14 days after I/R injury a significant reduction on the blood BUN level was observed in the vehicle group (34.06 mg/dl) compared to that of ischemia induced treated group (10.3mg/dl) (p < 0.05). In conclusion, administration of ascorbic acid for renal ischemic-reperfusion injury had influence on blood BUN level, but it was not revealed the influence on blood Cr and RI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Ascórbico
/
Nitrogênio da Ureia Sanguínea
/
Traumatismo por Reperfusão
/
Distribuição Aleatória
/
Ultrassonografia Doppler em Cores
/
Creatinina
/
Doenças do Cão
/
Nefropatias
/
Antioxidantes
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2006
Tipo de documento:
Artigo
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