Prognostic factors of neurological outcomes in late-preterm and term infants with perinatal asphyxia / 소아과
Korean Journal of Pediatrics
;
: 440-445, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-228479
ABSTRACT
PURPOSE:
This study aimed to identify prognostic factors of neurological outcomes, including developmental delay, cerebral palsy and epilepsy in late-preterm and term infants with perinatal asphyxia.METHODS:
All late-preterm and term infants with perinatal asphyxia or hypoxic-ischemic insults who admitted the neonatal intensive care unit of Inje University Sanggye Paik Hospital between 2006 and 2014 and were followed up for at least 2 years were included in this retrospective study. Abnormal neurological outcomes were defined as cerebral palsy, developmental delay and epilepsy.RESULTS:
Of the 114 infants with perinatal asphyxia, 31 were lost to follow-up. Of the remaining 83 infants, 10 died, 56 had normal outcomes, and 17 had abnormaloutcomes:
14 epilepsy (82.4%), 13 cerebral palsy (76.5%), 16 developmental delay (94.1%). Abnormal outcomes were significantly more frequent in infants with later onset seizure, clinical seizure, poor electroencephalography (EEG) background activity, lower Apgar score at 1 and 5 minutes and abnormal brain imaging (P<0.05). Infants with and without epilepsy showed significant differences in EEG background activity, clinical and electrographic seizures on EEG, Apgar score at 5 minutes and brain imaging findings.CONCLUSION:
We should apply with long-term video EEG or amplitude integrated EEG in order to detect and management subtle clinical or electrographic seizures in neonates with perinatal asphyxia. Also, long-term, prospective studies with large number of patients are needed to evaluate more exact prognostic factors in neonates with perinatal asphyxia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Índice de Apgar
/
Asfixia
/
Convulsões
/
Encéfalo
/
Terapia Intensiva Neonatal
/
Paralisia Cerebral
/
Estudos Prospectivos
/
Estudos Retrospectivos
/
Eletroencefalografia
/
Epilepsia
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Lactente
/
Recém-Nascido
Idioma:
Inglês
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2016
Tipo de documento:
Artigo
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