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Rates of Early Surgery and Associated Risk Factors in Crohn's Disease / 대한소화기학회지
The Korean Journal of Gastroenterology ; : 236-241, 2010.
Artigo em Coreano | WPRIM | ID: wpr-229037
ABSTRACT
BACKGROUND/

AIMS:

The individual course of Crohn's disease is diverse, and some patients may require bowel resection. The aims of this study were to determine the early surgery rate of Crohn's disease and to identify risk factors associated with early surgery in Korea.

METHODS:

Ninety six patients with Crohn's disease (68 men; median age at the time of diagnosis 25 years), who had been followed up more than a year, were retrospectively analyzed. Early surgery was defined as a bowel operation for Crohn's disease or its complications occurring within 3 years from diagnosis. Early surgery rate and risk factors for early surgery were identified.

RESULTS:

Fifteen patients (15.6%) underwent early surgery. The cumulative surgery rate was 8.6% after 6 months, 11.9% after 12 months, 14.1% after 18 months, and 16.7% after 24 to 36 months. Multivariate analysis revealed penetrating or stricturing behavior to be an independent risk factor for early surgery (p<0.001, Exp (B)=2.97 CI 1.39-6.37).

CONCLUSIONS:

The cumulative early surgery rate in Korean patients seems to be lower than Western patients. Penetrating or stricturing behavior is significantly associated with early surgery, requiring early aggressive medical treatments.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fatores de Tempo / Doença de Crohn / Fatores Sexuais / Análise Multivariada / Estudos Retrospectivos / Fatores de Risco / Constrição Patológica / República da Coreia Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Coreano Revista: The Korean Journal of Gastroenterology Ano de publicação: 2010 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fatores de Tempo / Doença de Crohn / Fatores Sexuais / Análise Multivariada / Estudos Retrospectivos / Fatores de Risco / Constrição Patológica / República da Coreia Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Coreano Revista: The Korean Journal of Gastroenterology Ano de publicação: 2010 Tipo de documento: Artigo