Factors Affecting Treatment Outcome of Graft Infection Following Penetrating Keratoplasty
Korean Journal of Ophthalmology
;
: 301-308, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-229271
ABSTRACT
PURPOSE:
To evaluate the factors affecting treatment outcome of graft infection following penetrating keratoplasty (PKP).METHODS:
In this retrospective study, 28 patients who underwent PKP between January 2005 and January 2013 and who were diagnosed with graft infection were classified into a treatment success group or a treatment failure group. Demographic and clinical characteristics, as well as the results of the microbiologic investigation, were analyzed and compared. A subsequent binary logistic regression analysis was performed to identify the prognostic factors affecting treatment outcome.RESULTS:
Graft infection occurred at a mean of 38.29 +/- 36.16 months (range, 1 to 96 months) after PKP. Seventeen patients developed bacterial keratitis, and 11 patients developed fungal keratitis. Overall, of the 28 patients, nine (32.1%) were classified in the treatment failure group. Multivariate analysis identified pre-existing graft failure (p = 0.019), interval longer than 72 hours between donor death and PKP (p = 0.010), and fungal infection (p = 0.026) as significant risk factors for treatment failure.CONCLUSIONS:
Pre-existing graft failure, extended interval between donor death and PKP, and fungal infection were important risk factors for treatment failure of graft infection following PKP.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Infecção da Ferida Cirúrgica
/
Infecções Oculares Bacterianas
/
Infecções Oculares Fúngicas
/
Estudos Retrospectivos
/
Fatores de Risco
/
Ceratoplastia Penetrante
/
Resultado do Tratamento
/
Sobrevivência de Enxerto
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
2015
Tipo de documento:
Artigo
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