Malignant Transformation of Benign Giant Cell Tumor / 대한골관절종양학회지
The Journal of the Korean Bone and Joint Tumor Society
;
: 14-19, 2012.
Artigo
em Coreano
| WPRIM
| ID: wpr-229311
ABSTRACT
PURPOSE:
We analyzed the oncologic outcome of the malignant transformed benign giant cell tumor of bone. MATERIALS ANDMETHODS:
Between January 2000 and February 2012, 5 cases were referred with suspicious malignant transformation of benign giant cell tumor. No patients underwent radiation therapy.RESULTS:
After referral, all patients received the wide excision of the tumor and its' pathologic diagnosis were osteosarcoma. As classified by the location of tumor lesion, 3 cases were located in the distal femur, 1 case was in the distal radius and 1 case was in the proximal femur. The average latent period between diagnosis of benign giant cell tumor and diagnosis of secondary malignant giant cell tumor was 49.2 months. (range, 24-126 months) The mean follow-up period was 21.6 months. There were subsequent local recurrence in 2 cases and 3 patients developed distant metastasis. All patients with lung metastasis were dead.CONCLUSION:
Malignant transformation of benign giant cell tumor of bone can be occurred within 5 years. Therefore, when benign giant cell tumor suspicious malignant transformation, it is necessary to do more aggressive treatment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Rádio (Anatomia)
/
Recidiva
/
Encaminhamento e Consulta
/
Osteossarcoma
/
Células Gigantes
/
Seguimentos
/
Tumor de Células Gigantes do Osso
/
Fêmur
/
Tumores de Células Gigantes
/
Pulmão
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Bone and Joint Tumor Society
Ano de publicação:
2012
Tipo de documento:
Artigo
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