Male Infertility with Reciprocal Translocation t(1;21)(q11;p13) / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 286-288, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-229485
ABSTRACT
Reports of male infertility associated with autosomal translocations are rare. Cases involving translocations between chromosomes 1 and 21 are even rarer. We describe an azoospermic male with a reciprocal translocation t(1;21)(q11;p13). The patient, a 31-year-old man with normal intelligence and phenotype, sought medical attention for evaluation of infertility. He had no history of familial infertility or congenital anomalies. Sperm counts on three occasions all revealed azoospermia. The cytogenetic analysis of blood showed a reciprocal translocation between the long arm of chromosome 1 and the short arm of chromosome 21 in all of the cells examined. We believe that the case presented here is the first reported male infertility with t(1;21) at these particular breakpoints.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenótipo
/
Braço
/
Contagem de Espermatozoides
/
Cromossomos Humanos Par 1
/
Cromossomos Humanos Par 21
/
Análise Citogenética
/
Azoospermia
/
Infertilidade
/
Infertilidade Masculina
/
Inteligência
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo
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