Vancomycin-resistant Enterococci in Singaporean hospitals: 5-year results of a multi-centre surveillance programme
Annals of the Academy of Medicine, Singapore
;
: 77-81, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-229597
ABSTRACT
<p><b>INTRODUCTION</b>Vancomycin-resistant enterococci (VRE) have emerged as one of the major nosocomial antimicrobial-resistant pathogens globally. In this article, we describe the epidemiology of VRE in Singaporean public hospitals in the 5 years following the major local VRE outbreak in 2005.</p><p><b>MATERIALS AND METHODS</b>A passive laboratory surveillance programme identified non-duplicate VRE isolates from 7 hospitals from 2006 to 2010. Descriptive statistics and time-series analysis was performed on all clinical VRE isolates for each individual hospital as well as for the combined dataset.</p><p><b>RESULTS</b>There were a total of 418 VRE isolates over 5 years, of which 102 isolates (24.4%) were from clinical cultures. Between 0.4% and 0.7% of all clinical enterococcal isolates were resistant to vancomycin. The overall incidence-density of VRE did not change over time in Singapore despite 2 separate outbreaks in tertiary hospitals in 2009 and 2010. Incidence-density of clinical VRE cases fell in 2 secondary hospitals, while another 2 hospitals experienced no significant VRE infections after 2008.</p><p><b>CONCLUSION</b>The prevalence of VRE clinical isolates remains low in Singaporean public sector hospitals. However, the presence of at least 2 outbreaks in separate hospitals over the past 5 years indicates the need for continued vigilance in order to prevent any further increase in VRE prevalence locally.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Singapura
/
Vancomicina
/
Vigilância da População
/
Infecção Hospitalar
/
Epidemiologia
/
Infecções por Bactérias Gram-Positivas
/
Enterococcus
/
Resistência a Vancomicina
/
Usos Terapêuticos
Tipo de estudo:
Estudo de rastreamento
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Annals of the Academy of Medicine, Singapore
Ano de publicação:
2012
Tipo de documento:
Artigo
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