Inter-ethnic differences--how important is it in cancer treatment?
Annals of the Academy of Medicine, Singapore
;
: 356-361, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-229653
ABSTRACT
It is now well recognised that there are inter-ethnic differences accounting for variations in both pharmacokinetics (PK) and pharmacodynamics (PD) of drugs, resulting in differences in drug responses. Treating physicians should be aware of pharmacogenetic differences that may exist between the races while extrapolating data generated from other populations to their own patients in order to ensure optimal treatment response and minimise toxicity. This is especially crucial in the practice of oncology where many anti-cancer drugs have narrow therapeutic indices. This paper discusses some commonly used drugs in cancer treatment where inter-ethnic differences in drug safety and efficacy are known to exist that are relevant to the Asian physician.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Etnicidade
/
Competência Clínica
/
Diversidade Cultural
/
Tratamento Farmacológico
/
Etnologia
/
Neoplasias
/
Antineoplásicos
Limite:
Humanos
Idioma:
Inglês
Revista:
Annals of the Academy of Medicine, Singapore
Ano de publicação:
2011
Tipo de documento:
Artigo
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