Genetic polymorphism of twelve Y chromosomal short tandem repeat loci in Chinese Hui ethnic group / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 594-597, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-229861
ABSTRACT
<p><b>OBJECTIVE</b>To obtain the genetic polymorphism of Y chromosomal short tandem repeat (Y-STR) loci in Ningxia Hui population.</p><p><b>METHODS</b>Blood samples were collected from 150 unrelated healthy male individuals of Ningxia Hui ethnic group. Twelve Y-STR loci were amplified in one tube by using the PowerPlex System STR Amplification Kit, and the genotypes were determined using Genescan and Genotype software of ABI377 DNA sequencer and the frequency of alleles and haplotypes of Ningxia Hui ethnic was obtained.</p><p><b>RESULTS</b>Seventy-five alleles were observed at 12 Y-STR loci. The frequency ranged from 0.0067-0.7067 and the gene diversity ranged from 0.4446-0.8877. Totally 148 different haplotypes were found, which were unique in 150 males. Two haplotypes were shared by 2 males respectively. The haplotype diversity was 0.9864.</p><p><b>CONCLUSION</b>The 12 Y-STR loci are highly polymorphic in Ningxia Hui population and are suitable for genetics and forensic research.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Haplótipos
/
Etnicidade
/
China
/
Repetições de Microssatélites
/
Cromossomos Humanos Y
/
Povo Asiático
/
Etnologia
/
Frequência do Gene
/
Genética
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2007
Tipo de documento:
Artigo
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