Identification of binding proteins to the PDZ domain of ERBIN / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 307-311, 2007.
Article
em Zh
| WPRIM
| ID: wpr-229983
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To identify the binding proteins to PDZ domain of ERBIN.</p><p><b>METHODS</b>Using PDZ domain of ERBIN as the bait, yeast two-hybrid technology was employed to screen the human lymphocyte leukemia cells MATCHMAKER cDNA library. The protein interaction was identified by immunoprecipitation.</p><p><b>RESULTS</b>A PDZ-binding protein, TAX1, was identified.</p><p><b>CONCLUSION</b>TAX1 is a novel binding protein to PDZ domain of ERBIN.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Ligação Proteica
/
Técnicas do Sistema de Duplo-Híbrido
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Linhagem Celular Tumoral
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Peptídeos e Proteínas de Sinalização Intracelular
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Proteínas Adaptadoras de Transdução de Sinal
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Imunoprecipitação
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Domínios PDZ
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Metabolismo
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Proteínas de Neoplasias
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2007
Tipo de documento:
Article