Clinical analysis of triple marker screening test for fetal Down syndrome in midtrimester of pregnancy-Low sensitivity of triple marker screening test / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 1914-1918, 1999.
Artigo
em Coreano
| WPRIM
| ID: wpr-23055
ABSTRACT
OBJECTIVE:
To assess the reliability of triple marker screening test in midtrimester pregnancy for fetal Down syndrome.METHODS:
From October 1, 1996 to May 31, 1998 at Nowon Eulji Hospital, 3700 Pregnant women underwent serum tiple marker screening for Down syndrome during 15-20weeks of gestational age. The results of serum triple marker screenig tests for Down syndrome and the outcomes of pregnancies were retrospectively assesed.RESULTS:
Sixty seven of 3700 cases(1.81%) were positive in screening test, and 3633(98.18%) cases were negative. Among 67 cases of positive screening test, 1 case(1.49%) was diagnosed as Down syndrome. Among 3633 cases of negative screening test, 4 cases(0.1%) were diagnosed as chromosomal abnormalies postnatally. Two of these 4 cases of chromosomal abnormalies were Down syndrome.CONCLUSION:
With this results, sensitivity of triple marker screeing test for Down syndrome is very low as 33.3%. In order to increase the sensitivity, some compensatory adjustment is required in triple marker screening test.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Segundo Trimestre da Gravidez
/
Resultado da Gravidez
/
Programas de Rastreamento
/
Estudos Retrospectivos
/
Idade Gestacional
/
Síndrome de Down
/
Equidae
/
Gestantes
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de rastreamento
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
1999
Tipo de documento:
Artigo
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