Histopathological changes in livers of patients with chronic severe hepatitis B / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 323-325, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-230606
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the histopathological features in livers of chronic severe hepatitis B (CSHB) patients.</p><p><b>METHODS</b>Histology of 42 livers was studied. HE, Masson, Sweet and D-PAS staining and cytokeratin 7, CD68 and proliferating cell nuclear antigen immuno-histochemical staining were used in the study.</p><p><b>RESULTS</b>In CSHB, the livers showed massive or submassive necrosis in a background of other histological changes of chronic hepatitis B. The characteristic pictures of these livers were necrosis of all the hepatocytes in some nodules, while in other nodules there were only patchy necroses of the parenchyma. In some other nodules the necrotic hepatocytes were all removed and only the scaffolding stroma remained. Meanwhile, regeneration of hepatocytes and bile ductules were also seen.</p><p><b>CONCLUSIONS</b>The liver histopathological changes in CSHB are identical, but not of the same degree as those of acute severe and subacute severe hepatitis B. In making differential diagnoses for liver aspiration biopsies of these patients, this fact should be kept in mind.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Coloração e Rotulagem
/
Hepatite B Crônica
/
Diagnóstico
/
Fígado
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Hepatology
Ano de publicação:
2007
Tipo de documento:
Artigo
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