Studies on alkaloids from Melodinus moraei / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 307-310, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-230954
ABSTRACT
To study the alkaloids from Melodinus moraei,seven compounds were separated and purified by column chromatography over silica gel, reverse phase silica gel and preparative HPLC. Their chemical structures were elucidated by MS and spectral data (1H-NMR, 13C-NMR) as scandine(1),tabersonine(2),melodinine N(3),melodinine P(4), melodinine T(5),19-epimeloscandonine(6),16-hydroxy-19S-vindolinine(7). Compounds 1-7 were isolated from M. moraei for the first time.The bioassays showed all tested samples displayed antitumor activity against the cell lines such as A549,PC-3,HGC-27 and HL-60.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2017
Tipo de documento:
Artigo
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