Study for association between high risk human papillomavirus and cervical lesions in the samples from opportunistic screening / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 89-91, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-231185
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the association between HPV genotypes and cervical lesion in Hybrid Capture 2 (HC2) HPV test positive samples.</p><p><b>METHODS</b>602 cervical samples randomly obtained detected as HPV positive by the HC2 high-risk probe cocktail were determined by polymerase chain reaction (PCR)-reverse dot blot (RDB), among them 344 participated Thinprep Cytology test.</p><p><b>RESULTS</b>569 (94.5%) samples were successfully amplified. The most common HPV genotypes were HPV16 (31.6%), 52 (16.7%), 58 (15.1%), 56 (8.1%), 39 (7.9%); HPV16 or HPV16/18 infection was significantly related to ASCUS, LSIL and HSIL; 24 samples suggested single HPV infection with the genotypes not available for HC2.</p><p><b>CONCLUSION</b>The most common HPV genotypes in random screening were HPV16, 52 and HPV58; Our data demonstrated the pseudo-positivity of HC2 test was 4.0%; HPV16 was a index for progression of HSIL.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Esfregaço Vaginal
/
Virologia
/
Doenças do Colo do Útero
/
Colo do Útero
/
China
/
Epidemiologia
/
Fatores de Risco
/
Classificação
/
Infecções por Papillomavirus
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2011
Tipo de documento:
Artigo
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