A concept of regulating tumor microenvironment immune and normalizing angiogenesis by Chinese medicine drug therapy for supporting zheng-qi to prop up root / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 201-204, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-231557
ABSTRACT
Antiangiogenic therapy can generate a "normalization window" for tumor vasculature. This normalization process prunes immature vessels and improves the integrity and function of the remaining vasculature by enhancing the perivascular cell and basement membrane coverage in tumor, therefor creates a window of opportunity for improved sensitivity to ionizing radiation and the delivery of chemotherapeutic drugs. It provides a rational basis for the combination therapy of traditional Chinese drugs with radiation and perhaps other forms of chemotherapy. Antiangiogenic therapy with the traditional Chinese drug interfering in the the mechanisms of the normalization window in humans maybe harness a new approach to improve the sensitivity of tumors to radio- and chemotherapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Medicamentos de Ervas Chinesas
/
Inibidores da Angiogênese
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Alergia e Imunologia
/
Microambiente Tumoral
/
Fitoterapia
/
Métodos
/
Neoplasias
/
Neovascularização Patológica
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2010
Tipo de documento:
Artigo
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