Study on the RNA of severe acute respiratory syndrome (SARS) associated coronavirus in the blood and excretion of convalescent patients with SARS / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 201-203, 2005.
Article
em Zh
| WPRIM
| ID: wpr-232107
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To examine the RNA of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) in the blood and excretion of convalescent patient with SARS for prevention and treatment of the disease.</p><p><b>METHODS</b>A total of 276 samples, including plasma, urine, feces and sputum, obtained from 23 convalescent patients with SARS were studied at 3 time-points at least 21 days after the onset of symptoms. RNA was extracted and nested reverse transcription-polymerase chain reaction (RT-PCR) was carried out using SARS-CoV specific primers.</p><p><b>RESULTS</b>Among the 276 samples, SARS-CoV RNA was detected in 6 cases (38.8%) by nested RT-PCR. The positive rates of SARS-CoV RNA was 5.8% in feces and 2.9% in sputum samples but SARS-CoV RNA was not detectable in plasma and urine of all the cases.</p><p><b>CONCLUSION</b>The existence of SARS-CoV RNA in the excretion of some convalescent patients with SARS showed that the excretion from these patients should be carefully treated whilthe re-transmission of SARS by which, should be further studied.</p>
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Índice:
WPRIM
Assunto principal:
Escarro
/
Virologia
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Sangue
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RNA Viral
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Convalescença
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Reação em Cadeia da Polimerase Via Transcriptase Reversa
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Síndrome Respiratória Aguda Grave
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Coronavírus Relacionado à Síndrome Respiratória Aguda Grave
/
Fezes
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2005
Tipo de documento:
Article