Association study between age-related macular degeneration and R1210C mutation of CFH gene in Chinese population / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 570-572, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-232254
ABSTRACT
<p><b>OBJECTIVE</b>A R1210C mutation of complement factor H (CFH) gene has been associated with age-related macular degeneration (AMD) in Caucasian population. This study was to verify above association in Han Chinese population.</p><p><b>METHODS</b>The mutation was detected by direct sequencing in 258 patients with wet AMD and 426 matched controls.</p><p><b>RESULTS</b>The R1210C mutation has not been identified in either sample.</p><p><b>CONCLUSION</b>The R1210C mutation in CFH gene is not associated with AMD in Han Chinese population.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fator H do Complemento
/
Genética
/
Degeneração Macular
/
Mutação
Tipo de estudo:
Estudo prognóstico
Limite:
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2012
Tipo de documento:
Artigo
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