HPLC tandem-mass spectrometric analysis of the chemical components and decomposition products of allicin extract of garlic / 药学学报
Acta Pharmaceutica Sinica
;
(12): 74-79, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-232594
ABSTRACT
To analyze the chemical components and decomposition products in allicin extract of garlic, the chemical components screening and identification were made with HPLC-MS/MS method by full scan TIC MS, HPLC retention time, product MS spectra and chemical reference standards. The stability of the extract in water and alcoholic solutions was also investigated. There were five major components in allicin extract which were all identified as thiosulfinates. The extract was stable for at least 3 months when stored at -20 degrees C as water solution, but obvious decomposition was observed with the increase of alcoholic concentration. The decomposition products were also identified by HPLC-MS/MS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plantas Medicinais
/
Ácidos Sulfínicos
/
Tiossulfatos
/
Química
/
Cromatografia Líquida de Alta Pressão
/
Espectrometria de Massas por Ionização por Electrospray
/
Estabilidade de Medicamentos
/
Espectrometria de Massas em Tandem
/
Alho
/
Metabolismo
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2009
Tipo de documento:
Artigo
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