Progress in the study of response surface modeling in investigation of drug-drug interaction in anesthetic drugs / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1171-1178, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-232622
ABSTRACT
As a novel and effective approach, response surface model is used in the study of drug-drug interactions. When two drugs are used simultaneously, this model can be applied to estimate the key characters of the response surface, to find the desired response region by optimal drugs combination, to explore the mechanism of drug-drug interactions, and thus to guide sound clinical application and reduce the risk and cost. In this article, the model's basic mathematical and pharmacological concepts are introduced, and its research progresses are reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Simulação por Computador
/
Midazolam
/
Alfentanil
/
Propofol
/
Modelos Estatísticos
/
Interações Medicamentosas
/
Sinergismo Farmacológico
/
Anestésicos
Tipo de estudo:
Fatores de risco
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2008
Tipo de documento:
Artigo
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