Comparison of anterior chamber depth measured by anterior segment optical coherence tomography and ultrasound biomicroscopy: a meta-analysis / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To compare the differences in the anterior chamber depth (ACD) measured by anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM).</p><p><b>METHODS</b>All studies pertaining to ACD measured by AS-OCT and UBM were collected from online databases. The assessment of methodological quality and data extraction from the included studies were performed independently by two reviewers for meta-analysis.</p><p><b>RESULTS</b>Eight studies involving 710 eyes were included in the analysis. The difference of ACD measurements between AS-OCT and UBM was not statistically significant in the overall patients included for analysis (SMD=0.19, 95%CI [0.00, 0.39]) or in the patients with primary angle-closed glaucoma (SMD=0.02, 95%CI[-0.04,0.19]).</p><p><b>CONCLUSIONS</b>The ACD measurements do not differ significantly between AS-OCT and UBM. Due to the relatively small number of the included studies and the patients involved, this conclusion needs further confirmation by high-quality studies involving larger sample sizes.</p>