Advances in the study of small molecule antagonists of chemokine receptors as anti-asthma agents / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1286-1290, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-232996
ABSTRACT
Asthma is a chronic inflammatory respiratory disease accompanied with airway inflammation, airway remodeling and bronchial hyperresponsiveness. Chemokines are important for the recruitment of immune cells to the lung, which play an important role in the formation and development of asthma. Targeting the chemokine receptors to anti-inflammation and anti-asthma is a new strategy and some candidate drugs are discovered recently. This review is focused on the development of chemokine receptor antagonists for anti-asthma, which will promote the compound designations.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Compostos de Fenilureia
/
Piperidinas
/
Piridazinas
/
Asma
/
Antiasmáticos
/
Receptores de Quimiocinas
/
Receptores CXCR4
/
Usos Terapêuticos
/
Tratamento Farmacológico
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2011
Tipo de documento:
Artigo
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