Progress in the study of allergic disease drugs targeting on IgE/FcepsilonRI signaling pathway / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1161-1166, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-233018
ABSTRACT
Allergic diseases have become global social health problems. The binding of IgE with its high affinity receptor FcepsilonRI plays a key step in I-type allergy. Recently, more and more key molecules on the IgE/FcepsilonRI signaling transduction pathway were to be the drug candidates against allergic diseases, with in-depth study of FcepsilonRI signal pathway gradually. The main drugs include molecule antibodies, peptides, vaccines, fusion proteins, small molecules, and other drugs related to IgE/FcepsilonRI. The recent progress in the study of mechanisms of representative drugs targeting on IgE/FcepsilonRI signaling pathway was reviewed in this article.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Pirimidinas
/
Proteínas Tirosina Quinases
/
Imunoglobulina E
/
Transdução de Sinais
/
Anticorpos Anti-Idiotípicos
/
Receptores de IgE
/
Antialérgicos
/
Usos Terapêuticos
/
Peptídeos e Proteínas de Sinalização Intracelular
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2011
Tipo de documento:
Artigo
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