Paclitaxel induced apoptotic genes and pathways alterations: a review / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 153-160, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-233259
ABSTRACT
Taxol has clinical efficacy on many malignant tumors, thus having a good market prospects. The anti-cancer mechanism of taxol is to arrest the cell cycle of tumor cells, leading to apoptosis. Based on our research over the years, we reviewed the latest developments in signaling pathways, the effects of related genes and proteins on apoptosis during paclitaxel-induced apoptosis process, including the paclitaxel-producing gene in microbial fermentation process, cyclin, telomerase of apoptosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Farmacologia
/
Transdução de Sinais
/
NF-kappa B
/
Paclitaxel
/
Apoptose
/
Fosfatidilinositol 3-Quinases
/
Sistema de Sinalização das MAP Quinases
/
Proteínas Quinases p38 Ativadas por Mitógeno
/
Tratamento Farmacológico
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2013
Tipo de documento:
Artigo
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