Candida tropicalis arthritis in a patient with acute leukemia / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1215-1218, 2008.
Artigo
em Inglês
| WPRIM
| ID: wpr-234264
ABSTRACT
Candida arthritis in patient with hematological malignancy is rare. A case of Candida tropicalis arthritis of knee occurred in a patient with acute monocytic leukemia was reported during the recovery phase of post chemotherapy myelosuppression and agranulocytosis. The patient was diagnosed as Candida tropicalis arthritis of knee according to the Candida tropicalis isolated from the synovial fluid. Itraconazole and amphotericin B were intravenously injected for therapy for 4 - 5 weeks based on the susceptibility test in vitro, which showed better efficacy. But the arthritis relapsed at 4 - 6 weeks after the drug withdrawal. The curative effect was found in patient after treatment with fluconazole injection and articular cavity douching with amphotericin B for 8 weeks. In conclusion, although Candida arthritis in patient with hematological malignancy is rare, it still occurred in the patient with hypoimmunity. The treatment emphasis showed be placed on the full dosage and full treatment course of antifungal agent.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Candidíase
/
Leucemia
/
Artrite Infecciosa
/
Candida tropicalis
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Microbiologia
/
Antifúngicos
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2008
Tipo de documento:
Artigo
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