The biological effect of Y-family DNA polymerases on the translesion synthesis / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 213-216, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-234676
ABSTRACT
A common DNA polymerase can replicate DNA which functions normally. However, if DNA suffers damage, the genome can not be replicated by a common DNA polymerase because DNA lesions will block the replication apparatus. Another kind of DNA polymerases in organism, Y-family DNA polymerases which is also called translesion synthesis (TLS) polymerases, can deal with this problem. Their main functions are bypassing the lesions in DNA, replicating the genome and saving the dying cells. This thesis presents a historical review of the literature pertinent to the structure, functions and roles of Y-family DNA polymerases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Dano ao DNA
/
Mutagênese
/
Classificação
/
Antígeno Nuclear de Célula em Proliferação
/
DNA Polimerase Dirigida por DNA
/
Reparo do DNA
/
Replicação do DNA
/
Genética
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2013
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS