Proapoptotic role of nuclear clusterin in brain / 대한해부학회지
Anatomy & Cell Biology
;
: 169-175, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-23482
ABSTRACT
Clusterin (CLU) is a multifunctional glycoprotein that has secretory and nuclear isoforms. The two isoforms are known to play opposite roles in cell survival/death. In this review, we summarize recent progress on the pro-apoptotic function of nuclear CLU in vitro and in vivo and discuss previous reports on the role of CLU in brain damage and neurodegeneration.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Encéfalo
/
Glicoproteínas
/
Apoptose
/
Isoformas de Proteínas
/
Clusterina
Idioma:
Inglês
Revista:
Anatomy & Cell Biology
Ano de publicação:
2011
Tipo de documento:
Artigo
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