Clinical study on effect of quyu xiaoban capsule on regression of atherosclerosis / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the effect of Quyu Xiaoban capsule (QXC) on regression and stabilization of atherosclerotic plaque with high-frequency ultrasound technique.</p><p><b>METHODS</b>Eighty patients with atherosclerosis (AS) were randomly divided into the treated group and the control group, level of blood lipids was measured, and intima-media thickness (IMT) and corrected value of image average echo intensity (AIIc%) were determined by ultrasound technique at the beginning of experiment and after being treated for six months.</p><p><b>RESULTS</b>The levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) were significantly decreased in the treated group after treatment (68.12 +/- 5.54 vs 61.43 +/- 5.37, P<0.05). The AIIc% of fatty atherosclerotic plaque was significantly increased after treatment (68.12 +/- 5.54 vs 61.43 +/- 5.37), and the change rate of AIIc% in the treated group was significantly different to that in the control group (10.9 +/- 5.1% vs 2.5 +/- 5.5%, P < 0.05).</p><p><b>CONCLUSION</b>QXC can significantly lower the blood lipids level, delay the progress and enhance the stability of atherosclerotic plaque.</p>