Topical melagenine for repigmentation in twenty-two child patients with vitiligo on the scalp / 中华医学杂志(英文版)

ABSTRACT

<p><b>BACKGROUND</b>The purpose of this study was to evaluate the efficacy of topical melagenine for repigmentation in child patients with vitiligo on the scalp.</p><p><b>METHODS</b>Twenty-two child patients with vitiligo on the scalp were treated with 1.2 mg/ml aqueous melagenine in combination with 20 minutes of infrared exposure twice daily.</p><p><b>RESULTS</b>In 4 patients (18.2%), melagenine treatment in combination with infrared exposure led to complete recovery; in 6 patients (27.3%), treatment was shown to be effective; in 8 patients (36.3%), treatment led to improvements in patient condition; and only 4 patients (18.2%) showed no response after 1 - 2 treatment sessions. The general effective rate of melagenine-infrared combination treatment was 45.5% for the children with vitiligo on the scalp, and treatment was accompanied by minimal side effects.</p><p><b>CONCLUSION</b>Melagenine may be efficacious and a safe treatment option for childhood vitiligo affecting the scalp.</p>