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Clinical observation on the treatment of male neoplastic anemia with Yixuesheng capsule combined with recombination human erythropoietin / 中国结合医学杂志
Chinese journal of integrative medicine ; (12): 63-65, 2009.
Artigo em Inglês | WPRIM | ID: wpr-236230
ABSTRACT
<p><b>OBJECTIVE</b>To explore the efficacy and mechanism of Yixuesheng capsule (, YXS) combined with recombination human erythropoietin (RHE) in treating male neoplastic anemia (NA).</p><p><b>METHODS</b>Sixty-five patients were randomized into two groups, the 33 patients in the treated group treated with a combined therapy of YXS and RHE, and the 32 in the control group treated with RHE alone, all for 12 weeks. Related clinical indexes, including hemoglobin (Hgb), red blood cell (RBC), hematocrit (HMC), testosterone (T), estradiol (E(2)) and prolactin (PRL), were measured before and after treatment.)</p><p><b>RESULTS</b>After treatment, Hgb in the treated group and the control group was 108+/-5 g/L and 104+/-8 g/L respectively, showing marked improvement as compared with that before treatment (P<0.01), and the improvement in the former was more significant than that in the latter (P<0.05). Further, the level of T was also increased in the treated group after treatment (P<0.05), and showed a significant difference from that of the control group (P<0.05).</p><p><b>CONCLUSIONS</b>YXS capsule combined with RHE shows a better therapeutic effect in treating NA than that of RHE alone, and the effect might be through stimulation by YXS of erythropoiesis which could promote the secretion of testosterone.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Hormônios Esteroides Gonadais / Sangue / Proteínas Recombinantes / Hemoglobinas / Cápsulas / Medicamentos de Ervas Chinesas / Eritropoetina / Resultado do Tratamento / Usos Terapêuticos Tipo de estudo: Ensaio Clínico Controlado Limite: Adulto / Idoso / Humanos / Masculino Idioma: Inglês Revista: Chinese journal of integrative medicine Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Hormônios Esteroides Gonadais / Sangue / Proteínas Recombinantes / Hemoglobinas / Cápsulas / Medicamentos de Ervas Chinesas / Eritropoetina / Resultado do Tratamento / Usos Terapêuticos Tipo de estudo: Ensaio Clínico Controlado Limite: Adulto / Idoso / Humanos / Masculino Idioma: Inglês Revista: Chinese journal of integrative medicine Ano de publicação: 2009 Tipo de documento: Artigo