The Relationship between ABO Blood Group Phenotypes and Seroprevalence of Infectious Disease in Korea / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 113-122, 2014.
Article
em Ko
| WPRIM
| ID: wpr-23669
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: The distribution of ABO and Rhesus D (RhD) blood group antigens differs according to race and region. Previous studies have reported that blood group type was associated with not only transfusion-related diseases but also various diseases, such as malignancy and infectious disease. However, true relationship of blood groups and many diseases remained controversial. The aim of this study was to determine whether ABO and RhD blood groups are correlated with several infectious diseases. METHODS: From January 2003 to December 2012, we retrospectively reviewed results for HBsAg, HCV Ab, HIV Ab, VDRL, HAV IgM, CMV IgM, EBV VCA IgM, and Clostridium difficile toxin A and B (CD toxin). We also reviewed ABO and RhD results of these patients. Data were analyzed using chi-square test and binary logistic regression test. Odds ratio and 95% confidence intervals were determined. RESULTS: A total of 109,898 medical records of ABO and HBsAg results were reviewed. Blood group type-A was more prone to have positive results with HBsAg, while blood group type-O was less affected (odds ratio 1.086, P=0.003, odds ratio 0.935, P=0.029, respectively). With 3,171 records of CD toxin, blood group type-O was more affected (odds ratio 1.247, P=0.027). The relationship of the other serologic results and blood groups was not statistically significant. CONCLUSION: Seroprevalence of HBsAg and CD toxin showed an association with blood group type. Blood group type-A had higher HBsAg seroprevalence than the other group. Blood group type-O was more prone to have CD toxin.
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WPRIM
Assunto principal:
Fenótipo
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Antígenos de Grupos Sanguíneos
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Imunoglobulina M
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Modelos Logísticos
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Razão de Chances
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Estudos Soroepidemiológicos
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Prontuários Médicos
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Doenças Transmissíveis
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Estudos Retrospectivos
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Clostridioides difficile
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
Korean Journal of Blood Transfusion
Ano de publicação:
2014
Tipo de documento:
Article