Effect of Campath-1H induction on immunosuppression in small intestine transplantation / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 199-201, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-237142
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of Campath-1H induction on immunosuppression in small intestine transplantation.</p><p><b>METHODS</b>Clinical data of a patient who underwent small intestine transplantation were retrospectively summarized.</p><p><b>RESULTS</b>Intraoperative Campath-1H induction by intravenous injection was administered. Triple immunosuppression(FK506, MMF and methylprednisolone) was used postoperatively. The lymphocyte and leukocyte decreased significantly following Campath-1H induction, and returned to normal after adjusting the dose of immunosuppressant and use of colony stimulating factor. There were no acute rejection, graft versus host disease, or severe infection during the immediate postoperative period. The patient recovered and discharged.</p><p><b>CONCLUSION</b>Intraoperative Campath-1H induction and postoperative triple immunosuppression using FK506, MMF, and methylprednisolone may prevent rejection and graft versus host disease in the early stage after small intestine transplantation.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transplante
/
Estudos Retrospectivos
/
Terapia de Imunossupressão
/
Usos Terapêuticos
/
Anticorpos Monoclonais Humanizados
/
Alemtuzumab
/
Rejeição de Enxerto
/
Imunossupressores
/
Intestino Delgado
Tipo de estudo:
Estudo observacional
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2011
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS