Polymorphisms of (CAG)n and(GGN)n repeats of androgen receptor gene among ethnic Hui and Han Chinese from Ningxia / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 365-369, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-237248
ABSTRACT
<p><b>OBJECTIVE</b>To compare the distribution of (CAG)n and (GGN)n repeats polymorphisms of androgen receptor (AR) gene between Hui and Han ethnic Chinese from Ningxia.</p><p><b>METHODS</b>Genotypes of above repeats were determined with DNA sequencing method.</p><p><b>RESULTS</b>The distribution of (GGN)n repeats was significantly different between the two ethnic groups (P< 0.01), though no such difference was detected with (CAG)n repeats (P> 0.05). Particularly, Han Chinese women carrying 23 GGN repeats were significantly fewer (48.4%) than Hui women (64.7%, P=0.01).</p><p><b>CONCLUSION</b>The distribution of GGN repeat is significantly differently among Hui and Han Chinese ethnics from Ningxia.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Dados de Sequência Molecular
/
Sequência de Bases
/
Receptores Androgênicos
/
China
/
Repetições de Trinucleotídeos
/
Expansão das Repetições de Trinucleotídeos
/
Grupos Populacionais
/
Povo Asiático
/
Alelos
Limite:
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2013
Tipo de documento:
Artigo
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